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Carcinogenesis | General

1. Butala, J., Moore, M., Cifone, M., Bankston, J., and Astill, B. et al. (1996). Oncogenicity study of di(isononyl) phthalate in rats.
The Toxicologist 30:202.

This abstract documented that liver tumors in rats caused by DINP are due to peroxisomal proliferation.

2. Butala, J., Moore, M., Cifone, M., Bankston, J., and Astill, B. (1997). Oncogenicity study of di(isononyl)phthalate in mice.
The Toxicologist 36:173.

This abstract documented that liver tumors in mice caused by DINP are due to peroxisomal proliferation.

3. David, R. Moore, M., Cifone, M., Finney, D., and Guest, D. (1999). Chronic Peroxisome proliferation and hepatomegaly associated with the hepatocellular tumorigenesis of di(2-ethylhexyl) phthalate and the effects of recovery.
Toxicological Sciences 50:195-205.

This paper documented that rodent liver tumors caused by DEHP are due to peroxisomal proliferation.

4. Lington, A., Bird, M., Plutnick, R., Stubblefield, W., and Scala, R. (1997). Chronic toxicity and carcinogenic evaluation of diisononyl phthalate in rats.
Fundamental and Applied Toxicology 36:79-89.

This paper documented that liver tumors in rats caused by DINP only occur at very high doses.

Last Updated: July 10, 2002



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