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1. Butala, J., David, R., Gans, G., McKee, R., and White, K. Evaluation of respiratory sensitization potential of phthalate esters. The Toxicologist 2003; 72, 51.
This paper reports that DINP, DIHP and BBP applied to the skin of mice did not stimulate production of cellular materials that are associated with the types of allergic reactions which typically lead to an asthma attack. These results indicate that DINP, DIHP and BBP are not likely to produce asthma.
2. Butala, J., David, R., Gans, G., McKee, R., and White, K. Evaluation of respiratory sensitization potential of DEHP. Toxicological Sciences 2003; 66(1-S) p. 22.
This abstract reports that DEHP applied to the skin of mice did not stimulate production of cellular materials that are associated with the types of allergic reactions which typically lead to an asthma attack. These results indicate that DEHP is not likely to produce asthma.
3. Medeiros, A., Devlin, D., and Keller, L. (1999). Evaluation of skin sensitization response of dialkyl (C6-C13) phthalate esters.
Contact Dermatitis 41:287-289.
This paper documented that major phthalates do not induce contact allergy in humans
4. Butala, J., David, R., Gans, G., McKee, R., and White, K. (2003). Evaluation of respiratory sensitization potential of phthalate esters. The Toxicologist 72: 51. (Abstract)
5. J. Butala, R. David, G. Gans, R. McKee, and K. White (2002). Evaluation of respiratory sensitization potential of DEHP. Toxicological Sciences 66:(1-S) p. 22. (Abstract)
6. Butala, J., David, R., Gans, G., McKee, R., Guo, T., Peachee, V., White, K., (2004). Phthalate Treatment Does Not Influence Levels of IgE or TH2 Cytokines in B6C3F1 mice. Toxicologist (accepted for publication).
This research showed that phthalates, when applied to the skin of mice, did not affect levels of immunological markers associated with respiratory allergy.
Last Updated: April 19, 2004
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